Can the vaccine cause an allergic reaction?

Although it is rare, the COVID-19 vaccines may cause mild allergic reactions in some people, like itching or rash. Extremely rarely, some people may have a severe allergic reaction like anaphylaxis.  People with a history of severe allergic reactions, such as anaphylaxis, to any component of a COVID-19 vaccine should not receive that vaccine. 

People who have had severe allergic reactions to other vaccines in the past should use caution and talk with their health care provider before deciding whether or not to get vaccinated.  People with a history of severe allergic reactions unrelated to any vaccine may get the COVID-19 vaccine. The health care provider administering your vaccine will monitor you for any allergic reactions you may have after getting vaccinated.

They will watch you for at least 15 minutes after the injection (or for 30 minutes if you have a history of anaphylaxis).  Sites administering COVID-19 vaccines should have health care staff, medications, and supplies for managing anaphylaxis (like epi-pens) on hand in case someone experiences a severe allergic reaction to the vaccine.

For more information about monitoring for severe allergic reactions, see the CDC’s Interim Considerations: Preparing for the Potential Management of Anaphylaxis at COVID-19 Vaccination Sites. CDC and FDA are continuously monitoring for allergic reactions in vaccine recipients. They will investigate reports quickly and update recommendations as more information becomes available.

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